Overview
SCIENTIFIC SCORE
Questionable
Based on 25 Researches
6.8
USERS' SCORE
Good
Based on 12 Reviews
8.2
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
5
Total Fat
0.5 g
< 1%**
Vitamin A (from Retinyl Palmitate and Cod Liver Oil)
750 mcg
83%
Vitamin D3 (from Cholecalciferol and Cod Liver Oil)
6.75 mcg (270 IU)
34%
Cod Liver Oil
650 mg
†
Top Medical Research Studies
9
Cod liver oil shows potential benefits
We explored the impact of cod liver oil on cardiovascular health, particularly its influence on heart disease processes. While marine fish consumption offers some benefits, high doses of fish oil can raise certain cholesterol levels and potentially increase risks.
In our study, we observed that when swine were given an atherogenic diet along with cod liver oil, important reductions in harmful monocyte adhesions and platelet clumping occurred. This suggests that fish oil may help improve blood flow and could be less risky than previously thought.
However, while promising, these effects from cod liver oil need more investigation to clarify their relevance in humans.
In our study, we observed that when swine were given an atherogenic diet along with cod liver oil, important reductions in harmful monocyte adhesions and platelet clumping occurred. This suggests that fish oil may help improve blood flow and could be less risky than previously thought.
However, while promising, these effects from cod liver oil need more investigation to clarify their relevance in humans.
Read More
9
We investigated whether cod liver oil could help with cardiovascular problems caused by diabetes in rats. Over 12 weeks, diabetic rats treated with cod liver oil showed improvements in weight gain and prevented harmful cholesterol and triglyceride levels. While it only partially controlled blood sugar, it significantly improved heart function. The oil also helped prevent damage in heart tissue and restored some normal responses in the heart to neurohormones. Although effective in these areas, it didn't eliminate all issues caused by diabetes.
Read More
8
We investigated the effects of cod liver oil on heart stability following a heart attack in rats. Over a 30-day period, we observed that cod liver oil significantly improved heart fibrillation thresholds and reduced irregular heartbeats. Specifically, it increased the heart's ability to withstand fibrillation by 50% and cut down on spontaneous extrasystoles by three times.
However, it didn’t show a significant impact on heart pressure or contraction speed. While these findings are promising for heart stability, they suggest that cod liver oil may not address all cardiovascular issues.
However, it didn’t show a significant impact on heart pressure or contraction speed. While these findings are promising for heart stability, they suggest that cod liver oil may not address all cardiovascular issues.
Read More
Most Useful Reviews
9
Relieves headaches
Omega 3 is essential for cardiovascular and nervous systems. Following Irina’s recommendation, I experienced significant benefits. My headaches and joint crunch have disappeared. I'm excited to continue using it!
Read More
9
Improves anxiety
After using NOW Foods Cod Liver Oil, my overall health improved remarkably. It reduced inflammation, particularly for my joints related to arthritis, and even decreased my anxiety and depression. The softgels are easy to swallow, and I appreciate the quality and packaging, which reflect its value for supporting cardiovascular disease.
Read More
9
Non-GMO source
NOW Cod Liver Oil is rich in Omega-3 fatty acids and serves as an excellent source of Vitamins A and D3. With strict quality control, it effectively aids overall health and supports cardiovascular disease prevention.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 25 Researches
6.8
- All Researches
9
We explored the impact of docosahexaenoic acid (DHA) from cod liver oil on heart health, especially following a heart attack (myocardial infarction). Using various models, we found that DHA increased heart cell survival under low oxygen conditions and lessened overall heart damage.
It also improved heart function and decreased scar tissue formation. By enhancing autophagy—a natural cell cleanup process—DHA showed promise in protecting heart tissue by activating important signaling pathways. Ultimately, our study suggests that DHA can help in heart recovery after serious damage.
It also improved heart function and decreased scar tissue formation. By enhancing autophagy—a natural cell cleanup process—DHA showed promise in protecting heart tissue by activating important signaling pathways. Ultimately, our study suggests that DHA can help in heart recovery after serious damage.
Read More
9
We investigated whether cod liver oil could help with cardiovascular problems caused by diabetes in rats. Over 12 weeks, diabetic rats treated with cod liver oil showed improvements in weight gain and prevented harmful cholesterol and triglyceride levels. While it only partially controlled blood sugar, it significantly improved heart function. The oil also helped prevent damage in heart tissue and restored some normal responses in the heart to neurohormones. Although effective in these areas, it didn't eliminate all issues caused by diabetes.
Read More
9
Cod liver oil shows potential benefits
We explored the impact of cod liver oil on cardiovascular health, particularly its influence on heart disease processes. While marine fish consumption offers some benefits, high doses of fish oil can raise certain cholesterol levels and potentially increase risks.
In our study, we observed that when swine were given an atherogenic diet along with cod liver oil, important reductions in harmful monocyte adhesions and platelet clumping occurred. This suggests that fish oil may help improve blood flow and could be less risky than previously thought.
However, while promising, these effects from cod liver oil need more investigation to clarify their relevance in humans.
In our study, we observed that when swine were given an atherogenic diet along with cod liver oil, important reductions in harmful monocyte adhesions and platelet clumping occurred. This suggests that fish oil may help improve blood flow and could be less risky than previously thought.
However, while promising, these effects from cod liver oil need more investigation to clarify their relevance in humans.
Read More
8
We assessed how taking marine omega-3 supplements, primarily cod liver oil, relates to coronary heart disease (CHD) mortality in a large group of men and women over 22 years.
Through three questionnaires, we observed that those who regularly used these omega-3 supplements had lower rates of CHD deaths compared to non-users.
While the results are promising, we must consider the possibility of other factors influencing this association. This suggests that more research is still needed to untangle these complex relationships.
Through three questionnaires, we observed that those who regularly used these omega-3 supplements had lower rates of CHD deaths compared to non-users.
While the results are promising, we must consider the possibility of other factors influencing this association. This suggests that more research is still needed to untangle these complex relationships.
Read More
8
We investigated how diet, particularly cod liver oil, affects blood pressure in elderly Icelanders aged 65 to 91. Using detailed food records and blood pressure measurements, we found that higher cod liver oil intake is linked to lower blood pressure.
This suggests possible health benefits for older adults. However, a significant number of participants displayed deficiencies in key nutrients like vitamin D and iron, underscoring the need for balanced diets in this age group.
This suggests possible health benefits for older adults. However, a significant number of participants displayed deficiencies in key nutrients like vitamin D and iron, underscoring the need for balanced diets in this age group.
Read More
User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Relieves headaches
Omega 3 is essential for cardiovascular and nervous systems. Following Irina’s recommendation, I experienced significant benefits. My headaches and joint crunch have disappeared. I'm excited to continue using it!
Read More
9
Improves anxiety
After using NOW Foods Cod Liver Oil, my overall health improved remarkably. It reduced inflammation, particularly for my joints related to arthritis, and even decreased my anxiety and depression. The softgels are easy to swallow, and I appreciate the quality and packaging, which reflect its value for supporting cardiovascular disease.
Read More
9
Non-GMO source
NOW Cod Liver Oil is rich in Omega-3 fatty acids and serves as an excellent source of Vitamins A and D3. With strict quality control, it effectively aids overall health and supports cardiovascular disease prevention.
Read More
7.5
Supports heart health
4 people found this helpful
Cod liver oil has multiple benefits for overall health. It reduces inflammation, eases arthritis pain, alleviates anxiety and depression, lowers diabetes risk, and supports the immune system. It's an excellent source of Vitamins A and D3, providing significant support for cardiovascular disease.
Read More
9
Supports cardiovascular health
2 people found this helpful
Cod liver oil is crucial for skin clarity, heart health, memory, and immunity against infections. It reduces cholesterol and triglycerides. Unlike other fish oils, it comes from cod liver, containing more Vitamins A and D, crucial for preventing cardiovascular disease.
Read More
Frequently Asked Questions
9
Relieves headaches
Omega 3 is essential for cardiovascular and nervous systems. Following Irina’s recommendation, I experienced significant benefits. My headaches and joint crunch have disappeared. I'm excited to continue using it!
9
Improves anxiety
After using NOW Foods Cod Liver Oil, my overall health improved remarkably. It reduced inflammation, particularly for my joints related to arthritis, and even decreased my anxiety and depression. The softgels are easy to swallow, and I appreciate the quality and packaging, which reflect its value for supporting cardiovascular disease.
9
Supports cardiovascular health
2 people found this helpful
Cod liver oil is crucial for skin clarity, heart health, memory, and immunity against infections. It reduces cholesterol and triglycerides. Unlike other fish oils, it comes from cod liver, containing more Vitamins A and D, crucial for preventing cardiovascular disease.
7.5
Supports bone health
NOW Foods Cod Liver Oil helps prevent cardiovascular disease and osteoporosis. It enhances central nervous system functioning and reduces chronic fatigue syndrome symptoms, positively affecting cartilage condition.
7.5
Improves joint pain
2 people found this helpful
I recommend fish oil for my sister's joint problems. May God heal her. It's vital for reducing inflammation and supporting heart health. She feels the difference and keeps repurchasing due to its positive impact on her condition.
7.5
Supports heart function
1 people found this helpful
I take cod liver oil for its omega-3 fatty acids, EPA and DHA. It has a long history of benefiting cardiovascular health. I recommend it for everyone looking to improve their immune system health.
9
Non-GMO source
NOW Cod Liver Oil is rich in Omega-3 fatty acids and serves as an excellent source of Vitamins A and D3. With strict quality control, it effectively aids overall health and supports cardiovascular disease prevention.
7.5
Supports heart health
4 people found this helpful
Cod liver oil has multiple benefits for overall health. It reduces inflammation, eases arthritis pain, alleviates anxiety and depression, lowers diabetes risk, and supports the immune system. It's an excellent source of Vitamins A and D3, providing significant support for cardiovascular disease.
7.5
Positive cardiovascular impact
Cod liver oil has a significant positive effect on cardiovascular disease, and long-term use can alleviate the issues associated with it.
References
- Shi Y, Li H, Wu T, Wang Q, Zhu Q, et al. Docosahexaenoic Acid-Enhanced Autophagic Flux Improves Cardiac Dysfunction after Myocardial Infarction by Targeting the AMPK/mTOR Signaling Pathway. Oxid Med Cell Longev. 2022;2022:1509421. 10.1155/2022/1509421
- Nilsen DWT, Myhre PL, Kalstad A, Schmidt EB, Arnesen H, et al. Serum Levels of Dihomo-Gamma (γ)-Linolenic Acid (DGLA) Are Inversely Associated with Linoleic Acid and Total Death in Elderly Patients with a Recent Myocardial Infarction. Nutrients. 2021;13. 10.3390/nu13103475
- Mal M, Kumar A, Meraj A, Devi A, Mañego AMB, et al. Role of Cod Liver Oil in Preventing Myocardial Infarction. Cureus. 2021;13:e16067. 10.7759/cureus.16067
- Kontostathi M, Isou S, Mostratos D, Vasdekis V, Demertzis N, et al. Influence of Omega-3 Fatty Acid-Rich Fish Oils on Hyperlipidemia: Effect of Eel, Sardine, Trout, and Cod Oils on Hyperlipidemic Mice. J Med Food. 2021;24:749. 10.1089/jmf.2020.0114
- Walquist MJ, Stormo SK, Østerud B, Elvevoll EO, Eilertsen KE. Cold-pressed minke whale oil reduces circulating LDL/VLDL-cholesterol, lipid oxidation and atherogenesis in apolipoprotein E-deficient mice fed a Western-type diet for 13 weeks. Nutr Metab (Lond). 2018;15:35. 10.1186/s12986-018-0269-8
- Lentjes MAH, Keogh RH, Welch AA, Mulligan AA, Luben RN, et al. Longitudinal associations between marine omega-3 supplement users and coronary heart disease in a UK population-based cohort. BMJ Open. 2017;7:e017471. 10.1136/bmjopen-2017-017471
- Arnarson A, Geirsdottir OG, Ramel A, Jonsson PV, Steingrimsdottir L, et al. [Dietary habits and their association with blood pressure among elderly Icelandic people]. Laeknabladid. 2012;98:515. 10.17992/lbl.2012.10.455
- Papageorgiou N, Tousoulis D, Psaltopoulou T, Giolis A, Antoniades C, et al. Divergent anti-inflammatory effects of different oil acute consumption on healthy individuals. Eur J Clin Nutr. 2011;65:514. 10.1038/ejcn.2011.8
- Ceylan-Isik A, Hünkar T, Aşan E, Kaymaz F, Ari N, et al. Cod liver oil supplementation improves cardiovascular and metabolic abnormalities in streptozotocin diabetic rats. J Pharm Pharmacol. 2007;59:1629.
- Vermel' AE. [Clinical application of omega-3-fatty acids (cod-liver oil)]. Klin Med (Mosk). 2005;83:51.
- Pedersen JI, Tverdal A, Kirkhus B. [Diet changes and the rise and fall of cardiovascular disease mortality in Norway]. Tidsskr Nor Laegeforen. 2004;124:1532.
- Kulakova SN, Gapparova KM, Pogozheva AV, Levachev MM. [Evaluation of the effects of fish and vegetable omega-3 PUFA complex on the erythrocyte fatty acid composition in patients with ischemic heart disease and impaired glucose tolerance]. Vopr Pitan. 1999;68:26.
- Vognild E, Elvevoll EO, Brox J, Olsen RL, Barstad H, et al. Effects of dietary marine oils and olive oil on fatty acid composition, platelet membrane fluidity, platelet responses, and serum lipids in healthy humans. Lipids. 1998;33:427.
- O'Shaughnessy M, Anderson GL, Acland RD, Barker JH. Platelet-derived thromboxane A2 decreases microvascular perfusion after arterial repair. Plast Reconstr Surg. 1997;99:834.
- Osterud B, Elvevoll E, Barstad H, Brox J, Halvorsen H, et al. Effect of marine oils supplementation on coagulation and cellular activation in whole blood. Lipids. 1995;30:1111.
- Kim DN, Eastman A, Baker JE, Mastrangelo A, Sethi S, et al. Fish oil, atherogenesis, and thrombogenesis. Ann N Y Acad Sci. 1995;748:474.
- Kim DN, Schmee J, Baker JE, Lunden GM, Sheehan CE, et al. Dietary fish oil reduces microthrombi over atherosclerotic lesions in hyperlipidemic swine even in the absence of plasma cholesterol reduction. Exp Mol Pathol. 1993;59:122.
- Meerson FZ, Belkina LM, Fu STs, Isaev VA. [Correction of disorders of cardiac electric stability in post-infarction cardiosclerosis using a diet enriched with polyunsaturated fatty acids]. Biull Eksp Biol Med. 1993;115:343.
- Barker JH, Gu JM, Anderson GL, O'Shaughnessy M, Pierangeli S, et al. The effects of heparin and dietary fish oil on embolic events and the microcirculation downstream from a small-artery repair. Plast Reconstr Surg. 1993;91:335.
- Checa-Ros A, Locascio A, Okojie OJ, Abellán-Galiana P, D'Marco L. Perirenal fat differs in patients with chronic kidney disease receiving different vitamin D-based treatments: a preliminary study. BMC Nephrol. 2025;26:119. 10.1186/s12882-025-04041-2
- Astani A, Maroofi A, Hekmatimoghaddam S, Sarebanhassanabadi M, Safari F. Sirtuin 1 mediates the pro-survival effects of vitamin D in angiotensin II-induced hypertrophy of H9c2 cardiomyoblasts. Mol Biol Rep. 2024;52:96. 10.1007/s11033-024-10168-6
- Qi RQ, Chen YF, Cheng J, Song JW, Chen YH, et al. Elabela alleviates cuproptosis and vascular calcification in vitaminD3- overloaded mice via regulation of the PPAR-γ /FDX1 signaling. Mol Med. 2024;30:223. 10.1186/s10020-024-00997-3
- France-Ratcliffe M, Harrison SL, Verma LA, Abdul-Rahim AH, McCallum L, et al. Vitamin D and cardiovascular outcomes in multiple sclerosis. Mult Scler Relat Disord. 2024;92:106155. 10.1016/j.msard.2024.106155
- Sadeghi M, Momeni A, Mirsaeidi FS, Jamalian M, Amirpour A, et al. The Effect of Vitamin D Deficiency Treatment on Lipid Profile and C-reactive Protein in Patients with Ischemic Heart Disease: Double-blind Randomized Clinical Trial. Adv Biomed Res. 2024;13:79. 10.4103/abr.abr_380_23
- Pan YX, Fu YC, Chen H, Zhao MY. [Association of serum 25(OH)D with cardiovascular risk-related indicators: cross-sectional analysis of NHANES]. Zhonghua Yu Fang Yi Xue Za Zhi. 2024;58:1388. 10.3760/cma.j.cn112150-20240519-00403
